Injectables being administered calmly by our Medical Director Dr Raul Cetto on a woman's face. She looks relaxed and at peace. Injectables being administered calmly by our Medical Director Dr Raul Cetto on a woman's face. She looks relaxed and at peace.
Aesthetic Medicine

HarmonyCa® Hybrid Biostimulator

Volume Restoration & Long-Term Skin Rejuvenation

A hybrid biostimulator that combines hyaluronic acid and calcium hydroxylapatite, designed to restore facial volume while supporting collagen production. This dual-action treatment provides an immediate lifting and hydrating effect, while progressively improving skin structure, firmness and elasticity over time, resulting in a more refined, naturally rejuvenated appearance.

HarmonyCa® is an advanced injectable treatment that combines the hydrating properties of hyaluronic acid with the collagen-stimulating effects of calcium hydroxylapatite. This dual approach provides both immediate volume restoration and progressive improvement in skin quality, supporting firmer, more resilient skin over time.

Unlike traditional dermal fillers that focus primarily on volume, HarmonyCa® works on multiple levels within the skin. The hyaluronic acid component delivers an instant smoothing and lifting effect, restoring subtle structure and hydration, while calcium hydroxylapatite supports the skin’s natural collagen production. This gradual process helps strengthen the skin’s underlying support, improving firmness, elasticity and overall skin integrity.

Over time, the skin appears more refined, supported and naturally rejuvenated. HarmonyCa® is particularly suited to those seeking a balanced approach to facial rejuvenation, enhancing volume where needed while improving skin quality for longer-term, natural-looking results.

Mid-face, cheeks and jawline

Immediate improvement in volume, hydration and contour, followed by progressive enhancement in skin firmness, elasticity and definition.

Results continue to improve over several weeks and are long-lasting, typically maintained for 12–18 months, and in some cases longer depending on the individual.

To prepare for HarmonyCa®, you may be advised to avoid alcohol, certain supplements and intense exercise in the days leading up to treatment to support a calm, predictable experience.

Following your session, mild swelling, tenderness or sensitivity can occur. Gentle aftercare, such as avoiding heat, pressure and vigorous activity, allows the treatment to settle naturally while supporting optimal results. As HarmonyCa® works progressively, improvements in skin quality will continue to develop over the following weeks.